Animal models in cardiovascular research

Animal Models in Cardiovascular Research: Hypertension and Atherosclerosis

Hypertension and atherosclerosis are among the most common causes of mortality in both developed and developing countries. Experimental animal models of hypertension and atherosclerosis have become a valuable tool for providing information on etiology, pathophysiology, and complications of the disease and on the efficacy and mechanism of action of various drugs and compounds used in treatment. ...

Animal ethics in Cardiovascular Research.

Animal research and cardiovascular surgery

Rev Bras Cir Cardiovasc | Braz J Cardiovasc Surg he invasion of the Royal Institute in São Roque, SP, on the 18th of October, in which tens of Beagle dogs were evacuated by activists, created a huge controversy, amplified by the wide dissemination in the media and on the internet. Moreover, the action of activists led to the closure of the lab. Not only that. Many institutions that use animals ...

Animal models in nutrition research.

Current knowledge in nutrition is based largely on the use of appropriate animal models together with defined diets. Numerous examples are cited where animal models have been used to solve nutrient x nutrient interactions, to evaluate bioavailability of nutrients and nutrient precursors, and to test for nutrient tolerances and toxicities. Advantages, disadvantages, and idiosyncrasies of various...

Animal models in endometriosis research.

Endometriosis is a common gynaecological disease, defined as the presence of endometrial tissue outside the uterus, causing pelvic pain and subfertility in approximately 10% of women of reproductive age. Current therapies lead to pain relief, however, do not address the causes and entail severe side effects. Still little is known about the pathogenic processes leading to the development and mai...